Although I was a little disappointed with Iron Man 3 (too much comedy and silliness), I still have to applaud it on it's SFX and action sequences! Also Guy Pearce.
I loved the visual effect of the Extremis Virus, and decided to take a leap out of my comfort zone and have a crack at replicating the effect when it goes overdrive!
Photoshop CS5 Painting.
About 3 days.
Airbrush + Texture brushes and environment effects for the charred skin from CGTextures.com
Dodge/Burn and Sharpen/Blur for finishing touches!